产品货号：
Z21471
中文名称：
NDUFB10抗体
英文名称：
Anti-NDUFB10 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NDUFB10 Antibody |
| 指标别名 | CI PDSW;Complex I PDSW;NDUFB10;PDSW |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | NDUFB10 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from the Internal region of human NDUFB10.at AA rangle:40-120 |
| 计算分子量 | 21KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 is an enzyme that in humans is encoded by the NDUFB10 gene.The protein encoded by this gene is an accessory subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I) that is not directly involved in catalysis.Mammalian complex I is composed of 45 different subunits.It locates at the mitochondrial inner membrane.This protein complex has NADH dehydrogenase activity and oxidoreductase activity.It transfers electrons from NADH to the respiratory chain.The immediate electron acceptor for the enzyme is believed to be ubiquinone.Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.[7] Initially,NADH binds to Complex I and transfers two electrons to the isoalloxazine ring of the flavin mononucleotide (FMN) prosthetic arm to form FMNH2.The electrons are transferred through a series of iron-sulfur (Fe-S) clusters in the prosthetic arm and finally to coenzyme Q10 (CoQ),which is reduced to ubiquinol (CoQH2).The flow of electrons changes the redox state of the protein,resulting in a conformational change and pK shift of the ionizable side chain,which pumps four hydrogen ions out of the mitochondrial matrix. |
| Uniprot ID | O96000 |
| 基因名全称 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 |
| 推荐稀释比 | WB,1:500～1:2000 |
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